The Trump administration is earning widespread praise from animal rights groups, lawmakers, and science advocates for taking major steps to phase out animal testing at both the Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA).

In a landmark announcement, the FDA declared its decision to end the requirement for animal testing in the development of antibody therapies and other drug research. Instead, the agency will promote the use of "organoids"—artificially grown 3D clusters of human cells that simulate organ behavior—as a humane and scientifically advanced alternative.

Kathy Guillermo, senior vice president at PETA, praised the move:

“PETA applauds the FDA’s decision to stop harming animals and adopt human-relevant testing strategies for evaluating antibody therapies. This is a significant step toward replacing the use of animals, something we’ve long advocated for."

Guillermo further emphasized the importance of eliminating animal use entirely, including controversial experiments on primates at federally funded research centers.

“We are calling on the FDA to fully embrace 21st-century science.”

On the same day, EPA Administrator Lee Zeldin announced that the agency would reinstate a 2019 policy, first introduced during President Trump's initial term, aimed at completely phasing out mammalian testing by 2035. The policy had seen delays under the Biden administration, but Zeldin confirmed a renewed commitment to its original timeline.

An EPA spokesperson, Molly Vaseliou, told The Washington Times:

“Administrator Zeldin is wholly committed to getting the agency back on track to eliminating animal testing.”

Animal welfare organizations welcomed the announcements. The White Coat Waste Project, which has previously exposed controversial animal experiments at government agencies, applauded the renewed effort to cut funding for what they describe as cruel and wasteful testing.

Justin Goodman, senior VP at White Coat Waste Project, stated:

“We applaud Administrator Zeldin and Commissioner Makary for picking up where Trump left off. This is great news for taxpayers and pet owners alike—it sends a strong message to federal agencies: Stop the money. Stop the madness.”

Kitty Block, President and CEO of Humane World for Animals, also responded positively but urged for meaningful implementation:

“We’re encouraged to see the EPA recommit to phasing out animal testing. But promises alone don’t spare lives. It's time to replace these cruel methods with modern, humane alternatives that the public overwhelmingly supports.”

The decisions by the FDA and EPA mark a major shift toward more ethical and effective scientific practices. By focusing on cutting-edge technologies and eliminating outdated animal-based methods, federal agencies are setting a precedent for innovation in the biomedical and environmental sciences.